Dr. Dennis Gross SkincareskincareTreat step

Dr. Dennis Gross Skincare Advanced Retinol + Ferulic Perfectly Dosed Retinol Extra Strength 0.5%

This extra-strength retinol treatment comes in convenient pads, delivering a potent dose of 0.5% pure retinol. It's designed to tackle visible signs of aging, including fine lines, wrinkles, and uneven texture, while also boosting radiance. The formula is enhanced with bakuchiol and rambutan to amplify retinol's benefits, and includes soothing ingredients like squalane and hyaluronic acid.

Sephora price

$42.00

Price matters most when you are trying to learn whether this lane belongs in your routine without turning the test into a luxury gamble.

Sephora reviews

4.7 / 5

About 99 reviews on the current Sephora source, so there is real volume behind the reputation.

Shoppers keep mentioning

Good for: Anti-AgingFragrance FreeVeganGood for: Uneven TextureRetinolPure Liquid Retinol: Smooths the look of lines and wrinkles.Bakuchiol and Rambutan: Reinforce the visibly age-defying and firming benefits of retinol.Squalane and Hyaluronic Acid: Soothe, hydrate, and lock in moisture.Dark SpotsFine Lines and Wrinklesand Uneven Texture

These are the shopper themes that keep showing up around this listing and shape why people open it in the first place.

Glass take

4.7 / 5 overall fit

A potent retinol treatment that effectively addresses signs of aging and texture concerns. Best for those already familiar with retinol.

Dr. Dennis Gross Skincare Advanced Retinol + Ferulic Perfectly Dosed Retinol Extra Strength 0.5%

Sephora snapshot refreshed April 23, 2026

Price, rating, review count, and source status come from Sephora. Glass adds the routine fit, overlap risk, and what to compare next.

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What Sephora says

What this product is supposed to do

A concentrated formula powered by 0.5 percent pure liquid retinol to visibly reduce lines and wrinkles, smooth texture, and boost radiance.

NormalDryCombinationand OilyDark SpotsFine Lines and Wrinklesand Uneven Texture

In the evening, apply pad to clean, dry skin, starting by wiping two to three times around your face, before moving down to your neck, décolleté, and shoulders.

Begin by limiting use to one to two times per week, gradually increasing frequency as tolerated.

For optimal results, follow with your Dr. Dennis Gross Skincare serum and moisturizer (each sold separately).

If you’ve never used a retinol product before, begin with the Advanced Retinol + Ferulic Perfectly Dosed Retinol Universal 0.2% (sold separately) and step up to the 0.5% formula as tolerated.

What Glass adds

What actually matters before you buy it

This is a high-performance retinol treatment for those seeking significant anti-aging results. The 0.5% concentration is best suited for individuals who have already built a tolerance to lower strengths of retinol. Its targeted approach to wrinkles and texture makes it a strong contender for mature or acne-scarred skin, but it requires a careful introduction into any routine.

Visible anti-aging results

Many users praise the product for its effectiveness in smoothing fine lines and wrinkles, and improving overall skin texture and radiance.

Importance of gradual introduction

Reviews frequently mention the necessity of starting with infrequent use and gradually increasing frequency to manage potential retinol-induced irritation.

Best for

When this is a smart buy

Mature skin
Acne-prone skin with texture concerns
Users with established retinol tolerance

Skip if

When this is the wrong lane

You are new to retinol
Your skin is currently experiencing active inflammation or sensitivity
You prefer a gentler, lower-strength retinol

Routine fit

Integrating into your routine

Apply this treatment to clean, dry skin in the evening. Start by using it only one to two times per week to allow your skin to adjust. As your tolerance builds, you can increase the frequency. Always follow with your preferred serum and moisturizer to maximize benefits and support hydration. If you're new to retinol, consider starting with a lower concentration like the Universal 0.2% version before moving up to this extra-strength formula.

Why it works

Where it earns the slot and where it does not

The useful question is not whether this product is good in a vacuum. It is whether it makes your routine easier to run or just adds one more bottle with a familiar ingredient on it.

What it actually does well

High concentration of pure retinol
Addresses multiple signs of aging
Convenient pad format
Includes supporting anti-aging and hydrating ingredients

Where it starts to feel redundant

Requires a slow introduction to avoid irritation
Not suitable for retinol beginners
Higher price point

Routine fit

Where it belongs in the stack

Evening treatment

This product is designed for nighttime use. Apply it after cleansing and before any serums or moisturizers to ensure optimal absorption and efficacy of the retinol.

Glass rating

How this formula scores in real life

4.7/ 5 overall

A potent retinol treatment that effectively addresses signs of aging and texture concerns. Best for those already familiar with retinol.

Efficacy

4.8 / 5

Users report noticeable improvements in fine lines, wrinkles, and skin texture with consistent use.

Ease of Use

4.5 / 5

The pre-dosed pads make application straightforward, though starting slowly is recommended.

Full ingredient breakdown

Every ingredient, what it does, and whether I care

Solvent

Water/Aqua/Eau

Badness

0.0 / 10

The base for many skincare formulations, dissolving other ingredients.

Usually helps with

All skin types

Watch for

None

Humectant

Pentylene Glycol

Badness

0.0 / 10

A moisturizing agent that also helps to preserve the product.

Usually helps with

All skin types

Watch for

None

Astringent

Hamamelis Virginiana (Witch Hazel) Water

Badness

1.0 / 10

A natural astringent that can help to tone the skin and reduce the appearance of pores. Can be drying for some.

Usually helps with

Oily, acne-prone skin

Watch for

Dryness, potential irritation for sensitive skin

Humectant

Hydroxyethyl Urea

Badness

0.0 / 10

A derivative of urea that effectively attracts and holds moisture in the skin.

Usually helps with

All skin types

Watch for

None

Solvent

Ethoxydiglycol

Badness

0.0 / 10

A solvent that helps to improve the penetration of other ingredients.

Usually helps with

All skin types

Watch for

None

Emollient

Caprylic/Capric Triglyceride

Badness

0.0 / 10

A skin-conditioning agent derived from coconut oil and glycerin that helps to replenish the skin's surface.

Usually helps with

All skin types

Watch for

None

Active

Retinol

Badness

7.0 / 10

A potent form of Vitamin A that accelerates cell turnover, reduces the appearance of wrinkles, fine lines, and uneven texture. Can cause irritation, redness, and peeling, especially when first introduced.

Usually helps with

Anti-aging, acne, texture

Watch for

Sensitivity, redness, peeling, sun sensitivity

Active

Bakuchiol

Badness

2.0 / 10

A plant-derived ingredient that offers retinol-like benefits, such as reducing the appearance of fine lines and improving skin texture, often with less irritation.

Usually helps with

Anti-aging, sensitive skin

Watch for

Generally well-tolerated

Antioxidant

Nephelium Lappaceum Leaf Extract

Badness

0.0 / 10

An extract from rambutan leaves, known for its antioxidant properties and ability to support skin firmness.

Usually helps with

All skin types

Watch for

None

Soothing Agent

Centella Asiatica Extract

Badness

1.0 / 10

Also known as cica or gotu kola, it has anti-inflammatory and wound-healing properties, helping to calm and soothe the skin.

Usually helps with

Sensitive, irritated skin

Watch for

None

Soothing Agent

Bisabolol

Badness

0.0 / 10

A component of chamomile, known for its anti-inflammatory and skin-calming properties.

Usually helps with

Sensitive, irritated skin

Watch for

None

Antioxidant

Ferulic Acid

Badness

2.0 / 10

A powerful antioxidant that helps protect skin from free radical damage and can stabilize other antioxidants.

Usually helps with

All skin types

Watch for

None

Humectant

Sodium Hyaluronate

Badness

0.0 / 10

The salt form of hyaluronic acid, it draws moisture into the skin for hydration and plumping.

Usually helps with

All skin types, dehydrated skin

Watch for

None

Emollient

Squalane

Badness

0.0 / 10

A skin-identical lipid that moisturizes and helps to improve skin's barrier function without clogging pores.

Usually helps with

All skin types, dry, oily skin

Watch for

None

Emollient

Linoleic Acid

Badness

0.0 / 10

An omega-6 fatty acid that is a component of the skin's natural barrier, helping to maintain hydration and suppleness.

Usually helps with

All skin types, dry, compromised skin

Watch for

None

Emollient

Linolenic Acid

Badness

0.0 / 10

An omega-3 fatty acid that helps to support the skin barrier and reduce inflammation.

Usually helps with

All skin types, dry, compromised skin

Watch for

None

Antioxidant

Soy Isoflavones

Badness

2.0 / 10

Plant compounds with antioxidant properties that may help improve skin's firmness and texture.

Usually helps with

Mature skin

Watch for

None

Antioxidant

Camellia Sinensis Leaf Extract

Badness

0.0 / 10

Green tea extract, rich in antioxidants that help protect the skin from environmental damage.

Usually helps with

All skin types

Watch for

None

Soothing Agent

Aloe Barbadensis Leaf Juice

Badness

0.0 / 10

Known for its soothing, hydrating, and anti-inflammatory properties.

Usually helps with

All skin types, sensitive, irritated skin

Watch for

None

Soothing Agent

Cucumis Sativus (Cucumber) Fruit Extract

Badness

0.0 / 10

Has cooling and soothing properties, often used to calm irritated skin.

Usually helps with

All skin types, sensitive skin

Watch for

None

Humectant

Sodium PCA

Badness

0.0 / 10

A component of the skin's natural moisturizing factor (NMF), it helps to attract and bind moisture to the skin.

Usually helps with

All skin types, dehydrated skin

Watch for

None

Exfoliant

Lactic Acid

Badness

4.0 / 10

An Alpha Hydroxy Acid (AHA) that exfoliates the skin's surface, improving texture and tone. Can increase sun sensitivity and cause mild stinging.

Usually helps with

Dull skin, texture concerns

Watch for

Sun sensitivity, potential irritation

Humectant

Rehmannia Glutinosa Root Extract

Badness

0.0 / 10

A traditional herbal ingredient used for its moisturizing properties.

Usually helps with

Dry skin

Watch for

None

Emollient

Phospholipids

Badness

0.0 / 10

Essential components of cell membranes, they help to restore the skin's barrier function and improve hydration.

Usually helps with

All skin types, dry, compromised skin

Watch for

None

Emollient

Sphingolipids

Badness

0.0 / 10

Lipids that are naturally found in the skin barrier, helping to maintain its integrity and prevent moisture loss.

Usually helps with

All skin types, dry, compromised skin

Watch for

None

Fragrance Ingredient

Farnesol

Badness

3.0 / 10

A fragrance component that can be a potential allergen for some individuals.

Usually helps with

None

Watch for

Allergic reactions, skin sensitivity

Soothing Agent

Anthemis Nobilis Flower Extract

Badness

0.0 / 10

Chamomile extract, known for its calming and anti-inflammatory properties.

Usually helps with

Sensitive, irritated skin

Watch for

None

Exfoliant

Mandelic Acid

Badness

4.0 / 10

An Alpha Hydroxy Acid (AHA) with a larger molecule size, making it gentler for exfoliation. Good for improving texture and tone, and can be helpful for acne.

Usually helps with

Acne-prone skin, sensitive skin, texture concerns

Watch for

Sun sensitivity, mild stinging

Humectant

Glycerin

Badness

0.0 / 10

A common and effective humectant that draws water into the skin, keeping it hydrated and soft.

Usually helps with

All skin types, dry skin

Watch for

None

Humectant

Butylene Glycol

Badness

0.0 / 10

A versatile ingredient that acts as a humectant and solvent, improving product texture and ingredient penetration.

Usually helps with

All skin types

Watch for

None

Emollient

Maltodextrin

Badness

0.0 / 10

A polysaccharide that can help to improve skin texture and provide a smooth feel.

Usually helps with

All skin types

Watch for

None

Cleansing Agent

Sodium Olivate

Badness

1.0 / 10

A salt derived from olive oil, used as a cleansing agent. Can be drying for some.

Usually helps with

Normal skin

Watch for

Dryness

pH Adjuster

Sodium Hydroxide

Badness

0.0 / 10

Used to adjust the pH of the product to be compatible with the skin.

Usually helps with

All skin types

Watch for

None

Emulsifier

Polysorbate 20

Badness

2.0 / 10

An emulsifier that can sometimes be contaminated with 1,4-dioxane, a potential carcinogen. Generally considered safe in low concentrations.

Usually helps with

All skin types

Watch for

Potential for irritation in sensitive individuals

pH Adjuster

Citric Acid

Badness

1.0 / 10

An Alpha Hydroxy Acid (AHA) used to adjust pH and provide mild exfoliation. Can increase sun sensitivity.

Usually helps with

Dull skin, texture concerns

Watch for

Sun sensitivity, potential irritation

Chelating Agent

Sodium Phytate

Badness

0.0 / 10

A plant-derived ingredient that helps to stabilize the formula by binding to metal ions.

Usually helps with

All skin types

Watch for

None

Antioxidant

Citrus Limon (Lemon) Peel Extract

Badness

2.0 / 10

Contains Vitamin C and antioxidants, but can also be phototoxic and irritating for some skin types.

Usually helps with

Brightening

Watch for

Sun sensitivity, irritation

Fragrance Ingredient

Citrus Aurantium Bergamia (Bergamot) Fruit Extract

Badness

4.0 / 10

A citrus extract that can be phototoxic and a potential skin irritant or allergen.

Usually helps with

None

Watch for

Sun sensitivity, irritation, allergic reactions

Fragrance Ingredient

Lavandula Angustifolia (Lavender) Flower/Leaf/Stem Extract

Badness

3.0 / 10

Contains fragrance compounds that can be irritating or allergenic for some individuals.

Usually helps with

None

Watch for

Allergic reactions, skin sensitivity

Preservative

Phenoxyethanol

Badness

2.0 / 10

A common preservative that can cause allergic reactions or irritation in some individuals.

Usually helps with

All skin types

Watch for

Skin sensitivity, allergic reactions

Preservative

Sodium Benzoate

Badness

1.0 / 10

A common preservative that can cause skin irritation or allergic reactions in sensitive individuals.

Usually helps with

All skin types

Watch for

Skin sensitivity, allergic reactions

Preservative

Potassium Sorbate

Badness

1.0 / 10

A preservative that is generally considered safe but can cause skin irritation in some individuals.

Usually helps with

All skin types

Watch for

Skin sensitivity

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FAQ

The fast answers people actually need

Is this product suitable for beginners to retinol?

No, this is an extra-strength formula (0.5% retinol) and is best suited for individuals who have already established a tolerance to retinol. Dr. Dennis Gross Skincare offers a Universal 0.2% version for those new to retinol.

How often should I use this retinol treatment?

It is recommended to start by using this product one to two times per week in the evening. Gradually increase the frequency as your skin builds tolerance. Always listen to your skin and adjust usage accordingly.

Can I use this retinol treatment with other active ingredients?

While this product contains other beneficial ingredients, it's generally advised to introduce potent actives like retinol slowly. Avoid using multiple strong exfoliants or actives on the same night initially. Always follow with a hydrating serum and moisturizer.

See If This Is Compatible With My Skin